Glucosamine and chondroitin are normal substances found in the body of living animals. They are at their highest concentration in cartilage. Unfortunately, through degradation during digestion and processing, almost all of the glucosamine in an animal’s diet is unavailable for use. The body, therefore, synthesizes most of its own glucosamine through a biochemical reaction utilizing glucose. In normal healthy animals the body is able to synthesize enough glucosamine to keep the existing cartilage healthy, but when the animal ages or there is damage to joint cartilage it cannot produce enough to keep up with the body’s needs. This is where a supplemental form of glucosamine is needed.

Glucosamine provides the building blocks to synthesize new cartilage. Glucosamine is the building block necessary for the production of the substances called glycosaminoglycans. The glycosaminoglycans are combined with hyaluronic acid to make the substance proteoglycans. The proteoglycans and collagen are the main structures of cartilage.